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Clio is located in southwest Barbour County in the southeast corner of Alabama and incorporated in 1890. Clio is the birthplace of Alabama governor George Wallace, Baseball Hall of Fame pitcher Don Sutton, and Elton B. Stephens, founder of EBSCO Industries. The Clio Museum of Moonshine features a small display on the town's history. Blue Springs State Park is located just east of the town and offers camping and picnic facilities, swimming in spring-fed pools, and sporting fields.